Journal: Frontiers in Endocrinology

Article Title: Discriminating early-stage diabetic retinopathy with subjective and objective perimetry

doi: 10.3389/fendo.2023.1333826

Figure Lengend Snippet: Clinical and demographic information of the persons with diabetes (mean ± SD).

Article Snippet: All patients underwent a single eye examination including a detailed history, a series of eye tests including BCVA determined using an ETDRS logMAR chart, 24-2 SWAP SITA Fast strategy (Humphrey Field Analyzer; Carl Zeiss Meditec, Inc., Dublin, CA), frequency doubling technology (Matrix) perimetry 24-2 ZEST strategy (Carl Zeiss Meditec, Dublin, Calif.), and optical coherence tomography (Spectralis, HRA+OCT; Heidelberg Engineering, Heidelberg, Germany).

Techniques:

Journal: Frontiers in Endocrinology

Article Title: Discriminating early-stage diabetic retinopathy with subjective and objective perimetry

doi: 10.3389/fendo.2023.1333826

Figure Lengend Snippet: Mean defect (MD) and pattern standard deviations (PSD) of the eyes of the PwT2D (mean ± SD).

Article Snippet: All patients underwent a single eye examination including a detailed history, a series of eye tests including BCVA determined using an ETDRS logMAR chart, 24-2 SWAP SITA Fast strategy (Humphrey Field Analyzer; Carl Zeiss Meditec, Inc., Dublin, CA), frequency doubling technology (Matrix) perimetry 24-2 ZEST strategy (Carl Zeiss Meditec, Dublin, Calif.), and optical coherence tomography (Spectralis, HRA+OCT; Heidelberg Engineering, Heidelberg, Germany).

Techniques:

Journal: Frontiers in Endocrinology

Article Title: Discriminating early-stage diabetic retinopathy with subjective and objective perimetry

doi: 10.3389/fendo.2023.1333826

Figure Lengend Snippet: Demographic variables determining OFA30 sensitivity and delay mean defect (MD) data.

Article Snippet: All patients underwent a single eye examination including a detailed history, a series of eye tests including BCVA determined using an ETDRS logMAR chart, 24-2 SWAP SITA Fast strategy (Humphrey Field Analyzer; Carl Zeiss Meditec, Inc., Dublin, CA), frequency doubling technology (Matrix) perimetry 24-2 ZEST strategy (Carl Zeiss Meditec, Dublin, Calif.), and optical coherence tomography (Spectralis, HRA+OCT; Heidelberg Engineering, Heidelberg, Germany).

Techniques:

Journal: Frontiers in Endocrinology

Article Title: Discriminating early-stage diabetic retinopathy with subjective and objective perimetry

doi: 10.3389/fendo.2023.1333826

Figure Lengend Snippet: The mean sensitivity and delay TD data for OFA15 (A-D) and OFA30 (E-H) . The means were computed at each 30-2 field location across the ETDRS 10 eyes (noDR, A, C, E, G ), and ETDRS 34 and 45 eyes (mmDR, B, D, F, H ). From the top down, the rows alternate: sensitivities, delays, sensitivities, delays (n.b. the calibration bar units of dB and ms). Before taking the means, right-eye data were flipped to left eye format; hence, the figures have the nasal field on the right. The four small central locations are magnified and presented at the bottom left of each panel. Generally, mmDR eyes (B, D, F, H) showed more severe changes than those with noDR. Peripheral damage appeared to be more evident for OFA30 fields.

Article Snippet: All patients underwent a single eye examination including a detailed history, a series of eye tests including BCVA determined using an ETDRS logMAR chart, 24-2 SWAP SITA Fast strategy (Humphrey Field Analyzer; Carl Zeiss Meditec, Inc., Dublin, CA), frequency doubling technology (Matrix) perimetry 24-2 ZEST strategy (Carl Zeiss Meditec, Dublin, Calif.), and optical coherence tomography (Spectralis, HRA+OCT; Heidelberg Engineering, Heidelberg, Germany).

Techniques:

Journal: Frontiers in Endocrinology

Article Title: Discriminating early-stage diabetic retinopathy with subjective and objective perimetry

doi: 10.3389/fendo.2023.1333826

Figure Lengend Snippet: Outcomes of linear mixed effects models showing the significant determinants of the OFA sensitivity total deviations (TDs) for: A) the OFA15 test, B) the OFA30 test.

Article Snippet: All patients underwent a single eye examination including a detailed history, a series of eye tests including BCVA determined using an ETDRS logMAR chart, 24-2 SWAP SITA Fast strategy (Humphrey Field Analyzer; Carl Zeiss Meditec, Inc., Dublin, CA), frequency doubling technology (Matrix) perimetry 24-2 ZEST strategy (Carl Zeiss Meditec, Dublin, Calif.), and optical coherence tomography (Spectralis, HRA+OCT; Heidelberg Engineering, Heidelberg, Germany).

Techniques:

Journal: Frontiers in Endocrinology

Article Title: Discriminating early-stage diabetic retinopathy with subjective and objective perimetry

doi: 10.3389/fendo.2023.1333826

Figure Lengend Snippet: Outcomes of linear mixed effects models showing the significant determinants of the OFA Delay Total Deviations (TDs) for: A) the OFA15 test, B) the OFA30 test.

Article Snippet: All patients underwent a single eye examination including a detailed history, a series of eye tests including BCVA determined using an ETDRS logMAR chart, 24-2 SWAP SITA Fast strategy (Humphrey Field Analyzer; Carl Zeiss Meditec, Inc., Dublin, CA), frequency doubling technology (Matrix) perimetry 24-2 ZEST strategy (Carl Zeiss Meditec, Dublin, Calif.), and optical coherence tomography (Spectralis, HRA+OCT; Heidelberg Engineering, Heidelberg, Germany).

Techniques:

Journal: Frontiers in Endocrinology

Article Title: Discriminating early-stage diabetic retinopathy with subjective and objective perimetry

doi: 10.3389/fendo.2023.1333826

Figure Lengend Snippet: Areas under receiver operating characteristic (AUROCs) expressed as percentages for different comparisons of Total Deviations outputs. Blue bars are for delay data, and yellow are for sensitivity data (legend). AUROC of 50% represents chance classification, and an AUC of 100% represents perfect discrimination. The x-axis labels of each plot give the test: SWAP 24-2, Matrix 24-2, OFA15, or OFA30 for Sensitivities (Sens) or Times-to-peak (Delay). The leftmost four comparisons were for discriminating ETDRS 10 eyes from the Mild to Moderate NPDR eyes (ETDRS 34 and 45): (noDR cf mmDR). The rightmost four comparisons were between normal control eyes (Cont) and ETDRS 34 and 45 eyes (mmDR), or Control cf. ETDRS 10 (noDR). The leftmost pair of yellow and blue bars give AUROCs for SWAP and Matrix 24-2 tests. The SAP versus OFA15 (A) and OFA30 (B) methods performed similarly, with delays performing better except for the (Cont cf noDR) comparison where sensitivity was better. The error bars represent SEM.

Article Snippet: All patients underwent a single eye examination including a detailed history, a series of eye tests including BCVA determined using an ETDRS logMAR chart, 24-2 SWAP SITA Fast strategy (Humphrey Field Analyzer; Carl Zeiss Meditec, Inc., Dublin, CA), frequency doubling technology (Matrix) perimetry 24-2 ZEST strategy (Carl Zeiss Meditec, Dublin, Calif.), and optical coherence tomography (Spectralis, HRA+OCT; Heidelberg Engineering, Heidelberg, Germany).

Techniques: Control, Comparison